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ANTIBODY ENGINEERING: METHODS AND PROTOCOLS

Antibody Engineering: Methods and Protocols (Methods in Molecular Biology)

Product Details
* Hardcover: 550 pages
* Publisher: Humana Press (December 2003)
* Language: English
* ISBN: 158829092

Abstract:
A set assemblage of different cutting-edge techniques for the generation, expression, optimization, and personation of recombinant antibodies. Readily duplicable protocols for advance procreation arrange from the cloning of manlike antibody genes to the activity and procreation of manlike recombinant antibodies by improvement approaches, molecular pass technologies and transgenic animals. Procedures are also described on restructuring antibody leads into monovalent, multivalent, and bispecific protection fragments for a panoramic difference of in vivo applications. State-of-the-art technologies are described for the personation of antigen-binding relationship and specificity with new applications in radioimmunotargeting, cancer immunotherapy, take abuse, and proteomics.

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